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Basic Metabolic Research and Critical Thinking
Provider: Faculty of Health and Medical Sciences

Activity no.: 3810-18-00-00
Enrollment deadline: 12/12/2017
Date and time19.01.2018, at: 08:00 - 09.02.2018, at: 16:00
Regular seats25
ECTS credits2.50
Contact personCarlotta Marasini    E-mail address: carlotta.marasini@sund.ku.dk

Aim and content
Learning objectives
A student who has met the objectives of the course will be able to:

1. Describe emerging themes in basic metabolic research
2. Have a foundation to critically analyze data from primary literature in basic metabolic research
3. Describe common methods used in the characterization of factors influencing metabolism and metabolic disorders
4. Explain how experiments in the primary literature investigating metabolism were performed
5. Evaluate whether or not a particular series of experiments warrants the conclusion made by the authors of a study

Content
The practice of clinical medicine is currently being revolutionized by rapid and extraordinary technological advances in molecular and cellular biology that have led to an unprecedented understanding of the molecular basis of human disease. Translating this knowledge into new clinical procedures and treatments demands a deeper understanding of the regulation of metabolism, and factors disposing individuals to metabolic disorders.
Metabolic disorders, including type 2 diabetes and obesity, affect hundreds of millions of people worldwide. Basic research investigating the genomic, gut microbiomic, molecular and physiological regulation of metabolism contributes to the progress of translational research within medicine and provides important insights that may be used in developing new initiatives for disease prevention, control and treatment.
The course brings together a group of experienced researchers to provide training on how to analyze data and think critically about state-of-the-art techniques for characterizing metabolic disorders and regulation of metabolism. Specifically, the content of the course will focus on discussing primary literature from current topics in the gut microbiome and metabolic health, the human genome and predisposition to metabolic disorders, endocrine signaling, and molecular regulation of metabolism.

Participants
Ph. D. –level students with a B.Sc. and/or M.Sc. degree in any biological science or chemistry are eligible to apply. The course is limited to a maximum of 25 participants.

Relevance to graduate programmes
The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH:

Basic Metabolic Research
Biostatistics and Bioinformatics

Language
English

Form
Students will participate in group literature discussion sessions led by leading researchers in several fields of Basic Metabolic Research, from the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen. Literature discussion sessions will take place weekly on Fridays for four weeks. A week before each session, a problem set of relevant scientific papers and questions based on their content will be provided. Students must then read the papers critically and submit a written report comprising the answers to the set questions before the discussion session. The discussion will then be based on the problem set. Evaluation (pass/fail) will take into account participation in discussion sessions and written work.

Course directors
Manimozhiyan Arumugam, Associate Professor, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen
Tuomas Kilpeläinen, Associate Professor, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen

Teachers
Group Leaders from the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen: http://metabol.ku.dk/

Dates
Three-hour discussion sessions on the following dates. Extensive reading of current literature (approx. 6-8 hours per session) and preparation of a written report are required in advance of each.
Friday 19 January, 2018
Friday 26 January, 2018
Friday 2 February, 2018
Friday 9 February, 2018

Course locations
Panum Institute, University of Copenhagen, Norre Alle 20, 2200 København

Registration
Please apply before 12 December, 2017. Use this form: http://tinyurl.com/RegiMetabolismDiscussion to provide your name, email address, the university and PhD program where you are currently enrolled, and a 150 word (max.) statement of your motivation for applying for this course. You will be notified about your registration by email soon after the deadline. Contact amelia.green@cpr.ku.dk with any questions.

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