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Advanced Genome and Cell Biology
Second title: Advanced Genome and Cell Biology
Provider: Faculty of Science

Activity no.: 5708-18-09-31 
Enrollment deadline: 15/08/2018
PlaceDepartment of Plant and Environmental Sciences
Date and time03.09.2018, at: 09:00 - 26.10.2018, at: 17:00
Regular seats50
ECTS credits7.50
Contact personHans Thordal-Christensen    E-mail address: htc@plen.ku.dk
Enrolment Handling/Course OrganiserHans Thordal-Christensen    E-mail address: htc@plen.ku.dk
Written languageEnglish
Teaching languageEnglish
Semester/BlockBlock 1
Scheme groupB
Scheme group noteDuration: 1 block
Exam requirements80% attendance
Exam formOral examination
Course workload
Course workload categoryHours
Lectures34.00
Project work16.00
Preparation154.00
Sum204.00
Content
This course includes lectures from the MSc course LBIK10135U Genome and Cell Biology.
The following areas are covered: Gene regulation, structure of genomes and their content of information, use of databases and experimental techniques for genome analysis. Gene control. Genome function. Gene and genome techniques. Membrane structure. Membrane transport. Intracellular compartments and the sorting of proteins. Signal transduction. Cell division. Cell cycle control, programmed cell death and autophagy.

Learning outcome
The purpose of this course is to bring students to an advanced level in cell biology. This level allows an easy start on a PhD project with cell biology content. Therefore the focus is on understanding principles and not on memorizing details since cell biology is an area of biology that evolves rapidly. The textbook, Molecular Biology of the Cell by Alberts et al., will form the basis for letures and poster work. In the course basic genetic mechanisms and elements like structure of chromosomes and genomes, DNA replication, transcription, translation and gene regulation will be covered. Furthermore, the course will deal with the internal structure of cells, membrane structures and transport of small molecules over membranes, intracellular compartments, transport between vesicles, cellular communication, autophagy and apoptosis as well as intracellular signalling.

After the course the student should be able to: 
Knowledge:
Describe the genetic and structural elements, genetic mechanisms and cellular communication of living cells.
Describe mechanisms involved in gene regulation in cells
Display overview of membrane structures, cellular compartments and transport of moleculas between compartments.
Describe cell division, cell cyclus control, autophagy and programmed cell death.

Skills:
Analyse and evaluate scientific papers which describe cellular processes of any kind.
Apply knowledge on the molecular biology of cells in the planning of own experiments.
Communicate know how in English on the structure and molecular mechanisms of living cells.

Competences:
Apply knowledge on the structure of molecular mechanisms of cells to further analyse problems within genome and cell biology. This level allows for an easy start on a PhD project with the cell biology content.

Literature

>Molecular Biology of the Cell by Alberts et al. 6th ed. (2015)
>Selected articles. Further information will be available. 

Teaching and learning methods

Lectures.
Article work: Group of students discuss larger articles recently published in a high impact scientific journal with individual teacher. The articles have been selected by the teachers to complete the cell biology area.

Workload
The course is organized in such way that it is highly recommended that the students have fundamental knowledge in cell biology, genetics, molecular biology and biochemistry. Students with little previous knowledge must be prepared to work hard

Remarks

If you would like to participate please:
1) Register online by clicking on "Apply" and
2) Send an e-mail to Hans Thordal-Christensen htc@plen.ku.dk  stating your motivations and CV (max. 10 lines)   

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