Graduate School of health and Medical Sciences

Glycobiology
Provider: Faculty of Health and Medical Sciences

Activity no.: 3428-19-00-00
	Enrollment deadline: 26/04/2019

Date and time	06.05.2019, at: 09:00 - 10.05.2019, at: 17:00
Regular seats	20
Course fee	7,200.00 kr.
Lecturers	Eric Paul Bennett
ECTS credits	4.50

Contact person	Miya Kudo Høffding E-mail address: mkudo@sund.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list. This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. COURSE DESCRIPTION This course is meant as a basic introduction to the structures, biosynthesis and function of complex carbohydrates. Protein glycosylation in eukaryotes is one of the most common forms of posttranslational modification, and carbohydrates on glycoproteins and glycolipids are involved in pleiotropic biological functions. During the course the glycosylation process in various eukaryotic cells will be illustrated, with particular focus on recombinant expression of glycoproteins. The course is organized in collaboration with The University in Lund and both lectures and “hands on” practical laboratory work will take place at the respective universities. The course will give insight to the structure and function of carbohydrate binding proteins and give examples of their role in normal and disease situations. The practical course will involve work with recombinant purified glycosyltransferase enzymes that will be used for in vitro glycosylation reactions. The sub-cellular compartment for glycosylation processes will be illustrated via immunocytochemical approaches using monoclonal antibodies against a panel of the estimated more than hundred human glycosyltransferases. The practical course will include “hands-on” use of reagents (lectins, antibodies, enzymes) and methods (chromatography, mass spec.) used to characterize carbohydrates. A deeper and broader theoretical understanding of important biological functions of carbohydrates and glycoproteins will be presented via lectures by national and international experts in the field, with particular emphasis on the relation between glycosylation defects and human diseases. Course title Glycobiology Learning objectives The objectives of the course are to give the student a basic introduction to the structures, biosynthesis and function of complex carbohydrates. In addition, the course will give insight to the structure and function of carbohydrate binding proteins and give examples of their role in normal and disease situations. A student who has met the objectives of the course will be able to: a. Describe the major mammalian glycosylation pathways b. Describe the biosynthetic complexity of the major glycosylation pathways c. Describe ways of identifying the most common mammalian glycan structures Content The following topics are covered on the course: General introduction to glycobiology, glycotechnology and glycogenetics, glycan function, glycosylation and diseases, carbohydrate binding molecules and glycan analysis, Participants No particular requirements Language English Form Lectures, discussions, exercises and demonstrations Course directors Katrine Ter-Borch Gram Schjoldager Assistant professor, Copenhagen Center for Glycomics, Institut for Cellulær og Molekylær Medicin, schjoldager@sund.ku.dk and Eric P. Bennett Associate professor, Copenhagen Center for Glycomics, Depertment of Odontology, epb@sund.ku.dk Course secretary Miya Kudo Høffding, ICMM, miya@sund.ku.dk Dates 6-10/5-2019 Course location Panum, Mærsk Tower, 10th floor Registration: Please register before 1/3-2019 Admission to PhD students from Danish and Swedish Universities will be allocated on a first-come, first-served basis and according to the rules in force. Applications from other participants will be considered after the last day of enrollment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

Click the search button to search Courses.

See which courses you can attend and when

Jan	Feb	Mar	Apr
May	Jun	Jul	Aug
Sep	Oct	Nov	Dec

New courses
Courses are published regularly. High demand courses are announced in spring and autumn.

Learn which courses are announced on fixed dates