The purpose of this course is to bring students to an advanced level in cell biology. This level allows an easy start on a PhD project with cell biology content. Therefore the focus is on understanding principles and not on memorizing details since cell biology is an area of biology that evolves rapidly. The textbook, Molecular Biology of the Cell by Alberts et al., will form the basis for letures and poster work. In the course basic genetic mechanisms and elements like structure of chromosomes and genomes, DNA replication, transcription, translation and gene regulation will be covered. Furthermore, the course will deal with the internal structure of cells, membrane structures and transport of small molecules over membranes, intracellular compartments, transport between vesicles, cellular communication, autophagy and apoptosis as well as intracellular signalling.After the course the student should be able to: Knowledge:Describe the genetic and structural elements, genetic mechanisms and cellular communication of living cells.Describe mechanisms involved in gene regulation in cellsDisplay overview of membrane structures, cellular compartments and transport of moleculas between compartments.Describe cell division, cell cyclus control, autophagy and programmed cell death.Skills:Analyse and evaluate scientific papers which describe cellular processes of any kind.Apply knowledge on the molecular biology of cells in the planning of own experiments.Communicate know how in English on the structure and molecular mechanisms of living cells.Competences:Apply knowledge on the structure of molecular mechanisms of cells to further analyse problems within genome and cell biology. This level allows for an easy start on a PhD project with the cell biology content.
>Molecular Biology of the Cell by Alberts et al. 6th ed. (2015)>Selected articles. Further information will be available.
Lectures.Article work: Group of students discuss larger articles recently published in a high impact scientific journal with individual teacher. The articles have been selected by the teachers to complete the cell biology area.
The course is organized in such way that it is highly recommended that the students have fundamental knowledge in cell biology, genetics, molecular biology and biochemistry. Students with little previous knowledge must be prepared to work hard
The course is terminated by an oral exam.
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Publication of new courses All planned PhD courses at the PhD School are visible in the course catalogue. Courses are published regularly.