Today, chromatography and mass spectometry are by far the most commonly used analytical techniques. A thorough understanding of the chromatographic theory, and operating mechanism of ionisation techniques and mass analysers is essential for method selection, development and optimisation. This is an Advanced course in chromatography and mass spectrometry for chemical analysis of organic compounds. The course is a natural extension of any basic course in analytical chemistry for everybody who is going to use modern hyphenated techniques such as GC-MS, LC-MS(MS) for analysis of complex mixtures.
The course covers chromatographic separation of small molecule organic compounds with special emphasize on the molecular mechanism and theory of analyte-column interactions for gas, supercritical fluid and liquid chromatography, and the theory of ionization, fragmentation, mass-to-charge separation, ion detection and data interpretation for all common mass spectrometers and ionization techniques. The theory is supplemented with laboratory exercises, computer simulations and guest-lectures of selected topics.
This course shares lectures, colloquia sessions, laboratory and theoretical exercises with the MSc course "Advanced Analytical Chemistry - Chromatography and Mass Spectrometry
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Publication of new courses All planned PhD courses at the PhD School are visible in the course catalogue. Courses are published regularly.