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Advanced Genome and Cell Biology
Provider: Faculty of Science

Activity no.: 5708-23-09-31 
Enrollment deadline: 28/08/2023
PlaceDepartment of Plant and Environmental Sciences
Date and time04.09.2023, at: 09:00 - 10.11.2023, at: 16:00
Regular seats50
ECTS credits7.50
Contact personHans Thordal-Christensen    E-mail address: htc@plen.ku.dk
Enrolment Handling/Course OrganiserHans Thordal-Christensen    E-mail address: htc@plen.ku.dk
Written languageEnglish
Teaching languageEnglish
Semester/BlockBlock 1
Scheme groupB
Scheme group noteDuration: 1 block
Exam requirements80% attendance during group presentations, PhD student lectures delivered
Exam formOral examination
Course workload
Course workload categoryHours
Lectures34.00
Project work16.00
Preparation154.00
Sum204.00
Content
This course is integrated with lectures and journal clubs from the MSc course LBIK10135U Genome and Cell Biology.
The course focuses on eukaryotic cells and the following areas are covered: Transcription, translation and protein folding. Chromatin dynamics and epigenetics. Control of gene expression. Membrane structures, transport and electric properties. Intracellular compartments and protein sorting. Intracellular vesicular traffic. Cell communication. The cell cycle. Normal and abnormal development. Energy conversion and mitochondria. Cytoskeleton. Comparative cell biology

Learning outcome
The purpose of this course is to bring students to an advanced level in genome and cell biology. The course is very useful for PhD projects that relates to cell biology. This area of biology develops rapidly, and therefore, the focus is on obtaining an overview and on understanding principles of how cells function as we address the above list of topics at an advanced level. The lectures are based on the textbook, Molecular Biology of the Cell by Alberts et al. In addition, a number of high impact articles will be discussed in detail in small groups.

After the course the student should be able to:
Knowledge:
Describe chromatin dynamics, gene structural elements, gene regulation mechanisms and signaling of living cells.
Display overviews of membrane structures, cellular compartments and transport of molecules between compartments.
Describe cell division and cell cycle control.

Skills:
Analyse and evaluate scientific papers which describe cellular processes of any kind.
Apply knowledge on the molecular cell biology in the planning of own experiments.
Communicate the structure and molecular mechanisms of living cells.

Competences:
Apply knowledge on the structure of molecular mechanisms of cells to further analyse problems within genome and cell biology. The course level allows for an easy start on a PhD project with cell biology content.

Literature
>Molecular Biology of the Cell by Alberts et al. 7th ed. (2022)
>Selected articles. Further information will be available.

Teaching and learning methods
Lectures.
Article work: Group of students discuss larger articles recently published in a high impact scientific journal with individual teacher. The articles have been selected by the teachers to complement the lectures to cover the cell biology area.

Workload
The course has a level that makes it highly recommended that the students have fundamental knowledge in cell biology, genetics, molecular biology and biochemistry. Students with little previous knowledge must be prepared for a challenging course.
The course is terminated by an oral exam.

Remarks
If you would like to participate please:
1) Register online by clicking on "Apply" and
2) Send an e-mail to Hans Thordal-Christensen htc@plen.ku.dk stating your motivations and CV (max. 10 lines)

*
UCPH discloses non-sensitive personal data to course reponsible/lecturers, if any. In addition, we will disclose non-sensitive personal data to the other participants in the course. Non-sensitive personal data includes names, job positions, institution names & addresses, telephone numbers and e-mail addresses.

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