Graduate School of health and Medical Sciences

Basic Kinetic Modeling in Molecular Imaging
Provider: Faculty of Health and Medical Sciences

Activity no.: 3601-17-00-00
	Enrollment deadline: 17/02/2017

Date and time	27.02.2017, at: 00:00 - 03.03.2017, at: 16:00
Regular seats	12
Course fee	6,480.00 kr.
Lecturers	Gitte Moos Knudsen
ECTS credits	3.60

Contact person	Dorthe Givard E-mail address: dorthe@nru.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School). Special rules apply for research year students enrolled at Faculty of Health and Medical Sciences at UCPH. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list. Course title Basic Kinetic Modeling in Molecular Imaging Learning objectives A student who has met the objectives of the course will be able to: a. Explain tracer kinetic principles in physiology, nuclear medicine and magnetic resonance imaging (MRI). b. Define Fick’s principle, compartments and rate constants c. Theorize on impulse response function, exponential functions and convolution d. Reflect on own project from a tracer kinetic perspective e. Use software for tracer kinetic modeling approaches f. Evaluate and select among kinetic models used for performing kinetic analysis of dynamic datasets Content Aspects covered: basic mathematics, introduction to SPECT, PET, and MRI, steady state, indicator diffusion, Fick's principle, clearance, extraction, mean transit time, convolution and impulse response, residue detection, Kety-Schmidt method, receptor kinetics and quantification, models of glucose consumption (Sokolof), water exchange and perfusion measurement, practical exercises on simulated and real datasets. The participants are encouraged to present and discuss their own projects. Participants PhD students in medicine, biophysics, physics, chemistry, and biology. Graduates with interest in this field. Max. 12 participants. Language English (unless there is only Danish speaking participants) Form Interactive teaching with examples and PC exercises. Course director Professor Gitte Moos Knudsen, Neurobiology Research Unit 6931, Rigshospitalet, Copenhagen, phone: (+45) 3545 6712, email: gmk@nru.dk; Professor Henrik Larsson, Functional and Diagnostic MR Unit, Glostrup, phone: (+45) 4323 2432, email: henrik.larsson@regionh.dk. Teachers Gitte Moos Knudsen, professor, DMSc, Neurobiology Research Unit, Rigshospitalet Henrik B.W. Larsson, professor, DMSc, Functional and diag. MR Unit, Glostrup Ling Feng, MSc, PhD, Neurobiology Research Unit, Rigshospitalet Adam Espe Hansen, MD, PhD, Dept. Clinical Physiology, Rigshospitalet Ian Law, MD, DMSc, Dept. Clinical Physiology, Rigshospitalet Lisbeth Marner, PhD, MD, Dept. Clinical Physiology, Rigshospitalet Esben Thade Pedersen, MR Dept, Hvidovre Hospital Claus Svarer, PhD, Neurobiology Research Unit, Rigshospitalet Dates Feb 27-March 3, 2017 Course location Rigshospitalet, The Rockefeller Complex, section 6911, Juliane Maries Vej 28, DK-2100 Copenhagen. Registration: Please register before Feb 12, 2017. Admission to PhD students from Danish universities will be allocated on a first-come, firstserved basis and according to the rules in force. Applications from other participants will be considered after the last day of enrollment.

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