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Basic Kinetic Modeling in PET and MR imaging
Provider: Faculty of Health and Medical Sciences

Activity no.: 3601-18-00-00 
Enrollment deadline: 01/02/2018
Date and time26.02.2018, at: 09:00 - 02.03.2018, at: 16:00
Regular seats15
Course fee6,480.00 kr.
LecturersGitte Moos Knudsen
ECTS credits3.60
Contact personDorthe Givard    E-mail address: dorthe@nru.dk
Enrolment Handling/Course OrganiserPhD administration     E-mail address: fak-phdkursus@sund.ku.dk

Aim and content
This course is free of charge for PhD students at Danish universities (except Copenhagen Business School). All other participants must pay the course fee.
Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list.

Learning objectives
A student who has met the objectives of the course will be able to:

1. Explain tracer kinetic principles in physiology, nuclear medicine and magnetic resonance imaging (MRI).
2. Define Fick’s principle, compartments and rate constants
3. Theorize on impulse response function, exponential functions and convolution
4. Reflect on own project from a tracer kinetic perspective
5. Use software for tracer kinetic modeling approaches
6. Evaluate and select among kinetic models used for performing kinetic analysis of dynamic datasets

Content
Aspects covered: basic mathematics, introduction to SPECT, PET, and MRI, steady state, indicator diffusion, Fick's principle, clearance, extraction, mean transit time, convolution and impulse response, residue detection, Kety-Schmidt method, receptor kinetics and quantification, models of glucose consumption (Sokolof), water exchange and perfusion measurement, practical exercises on simulated and real datasets. The participants are encouraged to present and discuss their own projects.

Participants
PhD students in medicine, biophysics, physics, chemistry, and biology. Graduates with interest in this field. Max. 12 participants

Relevance to graduate programmes
The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH:
All graduate programmes

Language
English (unless there is only Danish speaking participants)

Form
Interactive teaching with examples and PC exercises.

Course director
Professor Gitte Moos Knudsen, Neurobiology Research Unit 6931, Rigshospitalet, Copenhagen, gmk@nru.dk; Professor Henrik Larsson, Functional and Diagnostic MR Unit, Glostrup, henrik.larsson@regionh.dk.

Teachers
Gitte Moos Knudsen, professor, DMSc, Neurobiology Research Unit, Rigshospitalet
Henrik B.W. Larsson, professor, DMSc, Functional and diag. MR Unit, Glostrup
Ling Feng, MSc, PhD, Neurobiology Research Unit, Rigshospitalet
Adam Espe Hansen, MD, PhD, Dept. Clinical Physiology, Rigshospitalet
Ian Law, MD, DMSc, Dept. Clinical Physiology, Rigshospitalet
Lisbeth Marner, PhD, MD, Dept. Clinical Physiology, Rigshospitalet
Esben Thade Pedersen, MR Dept, Hvidovre Hospital
Claus Svarer, PhD, Neurobiology Research Unit, Rigshospitalet

Dates
Feb 26-March 2, 2018

Course location
Rigshospitalet, The Rockefeller Complex, section 6911, Juliane Maries Vej 28, DK-2100 Copenhagen.

Registration
Please register before 1 February , 2018

Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules.
Applications from other participants will be considered after the last day of enrolment.

Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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