Graduate School of health and Medical Sciences

Glycoanalysis & Glycoinformatics
Provider: Faculty of Health and Medical Sciences

Activity no.: 3427-19-00-00
	Enrollment deadline: 22/09/2019

Date and time	07.10.2019, at: 10:00 - 11.10.2019, at: 16:00
Regular seats	20
Course fee	6,960.00 kr.
Lecturers	Sergey Vakhrushev
ECTS credits	4.00

Contact person	Sergey Vakhrushev E-mail address: seva@sund.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School). Special rules apply for research year students enrolled at Faculty of Health and Medical Sciences at UCPH. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list. Course title Glycoanalysis and Glycoinformatics Course description Applications of analytical and synthetic chemistry are fundamental to elucidating the structures and expression patterns of complex biological molecules such as proteins and glycoconjugates, and understanding their functional interactions in order to exploit them effectively as targets of novel diagnostic and therapeutic strategies. This course is intended as an introductory survey of instrumental and chemical techniques currently being applied to proteomics, glycomics, and glycoproteomics, and to biological problems involving protein-carbohydrate interactions. The practical course will include mass spectrometry (MS) applied to the peptide and protein analysis, with a special focus on key post-translational modifications (PTMs), including N- and O-linked glycosylation. Coverage will include sample preparation, new developments in fragmentation of peptides and glycans for determination of sequence and PTM site occupancy, high throughput applications, biomarker analysis, and the basics of computational data analysis and bioinformatics. Learning objectives Students should expect to get an overview of carbohydrate structure and interactions, especially as these apply to glycoprotein biosynthesis and function; particular focus will be placed on current methods for detailed analysis of protein glycosylation, and for studying the impact of glycosylation on protein functional interactions. Content The following topics are covered on the course: General introduction to glycobiology, glycoproteomics, mass spectrometry, glycoinformatics, and glycan analysis Participants PhD students engaged in projects that require knowledge of the structural chemistry and intermolecular interactions of glycoconjugates, current methods for analysis of protein glycosylation, and their applications in the field of biomedicine. The course is relevant for all graduate programmes. Language English Form Lectures, discussions, exercises and demonstrations Course director Sergey Vakhrushev Associate professor, Copenhagen Center for Glycomics, Institut for Cellulær og Molekylær Medicin, seva@sund.ku.dk Teachers Sergey Vakhrushev, Hiren Joshi, Adnan Halim, and invited lecturers Course secretary Miya Kudo Høffding, ICMM, miya@sund.ku.dk Dates 7-11/10/2019 Course location Panum, Mærsk Tower, 10th floor Registration: Please register before 1/9-2019 Admission to PhD students from Danish and Swedish Universities will be allocated on a first-come, first-served basis and according to the rules in force. Applications from other participants will be considered after the last day of enrollment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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