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Research metodology in Acute Hematology and Transplantation
Provider: Faculty of Health and Medical Sciences

Activity no.: 3668-19-00-00 
Enrollment deadline: 14/02/2019
Date and time14.03.2019, at: 00:00 - 15.03.2019, at: 16:00
Regular seats20
Course fee2,160.00 kr.
LecturersHenrik Sengeløv
ECTS credits1.00
Contact personHenrik Sengeløv    E-mail address: sengelov@rh.dk
Enrolment Handling/Course OrganiserPhD administration     E-mail address: fak-phdkursus@sund.ku.dk

Aim and content
This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee.

Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list.

Course title
Research metodology in Acute Hematology and Transplantation

Learning objectives

1. Knowledge of different approaches to perform clinical studies in acute ill and transplant patients.
2. Knowledge of regulations in civil data protection, access to patient data.
3. Knowledge of ethical issues when including a healthy donor in the treatment.
4. Knowledge of the biological mechanisms in GVHD, and treatment thereof and evaluation of clinical studies in this field.

A student who has met the objectives of the course will be able to:
• Ability to identify clinical research methodologies; randomized study, retrospective study, register study
• Have insight in the very first “data grooming”, when obtaining data from databases
• Have insight in the ethical dilemmas when including a healthy donor in the treatment
• Demonstrate knowledge of the civil data protection system in context of clinical studies


Content
Clinical pathogenesis and treatment of:
Sepsis syndrome
Febrile neutropenia
Graft versus host disease
Clinical decision in bone marrow transplantation
Design and statistical methods in clinical research
Research after the phd-grade

The above mentioned topics are covered by the program as follows:

Acute hematology
Clinical research in patients with acute hematologic illness poses several methodological and practical problems. The logistics are difficult, both in terms of achieving patient consent and sampling of biological material. The course introduces the students to planning and the academic process both in a randomized study, and in a large register study with untrimmed data to start with. Furthermore, the current regulations for data protection and access to patient data are reviewed. The ultimate goal is to encourage the students to start clinical studies on bases of their phd-thesis, preferably randomized.

Transplantation
Allogeneic hematologic stem cell transplantation (HSCT) is an expanding field in hematology. Hematologic diseases resistant for chemotherapy can be cured by transplantation, but it comes with a price; infections and attack of the transplanted immune system (graft versus host disease, GVHD) results in morbidity and mortality of the transplant patient. In this course, the student will learn and discuss ethical issues in using a donor in the treatment, the organization of HSCT in Denmark, donor search from registers, and different approaches to clinical research comprising both clinical data and basic science.

Research
A special session is included in which the mentors will discuss opportunities and obstacles in research after the phd. The students are encouraged to participate actively with questions and future plans.

Participants
Describe the target group of the course and required qualifications (if any) by the participating PhD students.

Admission to PhD students from Danish universities will be allocated on a first-come, first-served basis and according to the rules in force. Applications from other participants will be considered after the last day of enrollment.

Relevance to graduate programmes
The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH:

Clinical Cancer Research
Clinical Research
Immunology and Infectious Diseases

Language
English or Danish. Note that all courses have to be provided in English if required by non-Danish participants.

Form
Lectures
Discussions
Presentations by phd-students of their project

Course director
Associate professor Henrik Sengeløv, Department of Clinical Medicine, University of Copenhagen, chief physician, Dept. of Hematology, Rigshospitalet, Copenhagen.
Mail: sengelov@rh.dk
-in collaboration with the Danish Haematological Research Educational Network (Dansk Hæmatologisk Forskerskole Netværk)

Teachers
Associate professor, DMSc, Henrik Sengeløv, University of Copenhagen, dept. of Hematology, Rigshospitalet
Professor, DMSc, Kirsten Grønbæk, University of Copenhagen, dept. of Hematology, Rigshospitalet
Professor, DMSc, Niels Abildgaard, University of Southern Denmark, dept of hematology, Odense University Hospital
Professor, DMSc, Fransesco d’Amore, University of Aarhus, Dept of Hematology, Aarhus University Hospital

Dates
14.-15. march 2019

Course location
“Huset”, Middelfart. The course is held in connection with the Annual meeting in the Danish society of Hematology, which is held at Hindsgavl castle, next to “Huset”.

Registration
Please register before February 12, 2019

Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules.
Applications from other participants will be considered after the last day of enrolment.

Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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