Graduate School of health and Medical Sciences

Genome Maintenance & Diseases
Provider: Faculty of Health and Medical Sciences

Activity no.: 3252-19-00-00	There are no available seats
	Enrollment deadline: 01/10/2019

Date and time	18.11.2019, at: 09:00 - 21.11.2019, at: 17:00
Regular seats	20
Course fee	3,840.00 kr.
Lecturers	Claus Sørensen Julien Duxin Niels Mailand
ECTS credits	3.20

Contact person	MoMed Team E-mail address: momed@bric.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1.Understand and describe the main pathways of genome maintenance and their molecular links to cancer and other human diseases 2.Understand the benefits and limitations of different model systems and technologies to study genome maintenance processes 3.Analyze experimental data and communicate scientific hypothesis and results 4.Gain a broad perspective of how basic research can be translated into the clinic Content 1.Introduction to genome maintenance pathways and diseases 2.Mechanisms and experimental methods: DNA replication & DNA-crosslink repair Replication stress, checkpoint signaling and imaging technologies DNA damage response, protein signaling, and screening technologies Chromosome Maintenance and Cell cycle progression 3.Physiology and model organisms: Modeling genome maintenance diseases in mice Genome instability in germline cells 4.From basic research to the clinic: Drug design, validation and approval Novel technologies in disease diagnosis Disease treatment Participants Participants must be enrolled in a graduate program at the Faculty of Health and Medical Science and have an interest in mechanisms of genome maintenance and diseases. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: All Graduate programs of Health and Medical Science Language English Form Lectures Group work and discussions Course director Claus Storgaaard Sørensen, Associate Professor, BRIC, University of Copenhagen, claus.storgaard@bric.ku.dk Niels Mailand, Professor, NNF center for Protein Research, University of Copenhagen, niels.mailand@cpr.ku.dk Julien Duxin, Associate Professor, NNF center for Protein Research, University of Copenhagen, Julein.duxin@cpr.ku.dk Teachers Claus Storgaaard Sørensen, Associate Professor, BRIC, University of Copenhagen, claus.storgaard@bric.ku.dk Niels Mailand, Professor, NNF center for Protein Research, University of Copenhagen, niels.mailand@cpr.ku.dk Julien Duxin, Associate Professor, NNF center for Protein Research, University of Copenhagen, Julein.duxin@cpr.ku.dk Luis Toledo, Associate Professor, Center for Chromosome Stability, , University of Copenhagen, ltoledo@sund.ku.dk Andres Lopez-Contreras, Associate Professor, Center for Chromosome Stability, , University of Copenhagen, ajlopez@sund.ku.dk Eva Hoffmann, Professor, Center for Chromosome Stability, University of Copenhagen, eva@sund.ku.dk Oscar Fernandez-Capetillo, Professor, Karolinska Institutet, oscar.fernandez-capetillo@ki.se Fabian Coscia, Postdoc, , NNF center for Protein Research, University of Copenhagen, Fabian.coscia@cpr.ku.dk Peter Bouwman, Postdoc, Netherlands Cancer Institute, p.bouwman@nki.nl Kirsetn Grønbæk, Professor, BRIC kirsten.gronbek@bric.ku.dk Dates November 18 to November 21, 2019 Course location Panum Registration Please register before October 1st, 2019 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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