Graduate School of health and Medical Sciences

Translational hematology
Provider: Faculty of Health and Medical Sciences

Activity no.: 3673-19-00-00
	Enrollment deadline: 01/09/2019

Date and time	21.10.2019, at: 09:00 - 25.10.2019, at: 16:00
Regular seats	20
Course fee	5,520.00 kr.
Lecturers	Bo Porse
ECTS credits	4.00

Contact person	MoMed Team E-mail address: momed@bric.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list. Course title: Translational hematology Learning objectives A student who has met the objectives of the course will be able to: 1. Understand disease evolution in MDS and AML 2. Understand how insights into basic disease mechanism may govern the development on novel therapeutic strategies 3. Understand the challenges in the clinical management of MDS and AML Content The course will describe basic concepts of hematopoiesis and how this process goes awry in hematological malignancies such as myelodysplastic syndrome and acute myeloid leukemia. Specific emphasis will be put on the role of stem cells in the initiation and maintenance of disease. We will also discuss the continuum of disease development ranging from clonal hematopoiesis to full-blown leukemia and introduce current and emerging strategies for the clinical handling of MDS and AML. Finally, we will describe basic research efforts into identification of novel targets using both functional genomics and drug screening. Participants The course targets PhD students interested in how research into basic disease mechanisms may be translated to clinical use. As such, both PhD students within medical sciences and biological sciences may be potential candidates for the course. The students will be exposed to primary scientific literature and should be comfortable with that. A prior interest and knowledge of hematology and/or stem cells is beneficial. The course is limited to 24 participants. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: Molecular Mechanisms of Disease Clinical Cancer Research Biostatistics and Bioinformatics Pharmaceutical Sciences (Drug Research Academy) Language English Form We will combine lectures, group work, discussions and journal clubs. Lectures (2-3 per day) will be mixed with the other activities. Students will be presenting their own work and how it relates to the field on the first day. Journal clubs (6) will be hosted by invited teachers on key scientific articles relating to their presentations. Students need to have read the articles beforehand. A group work task (groups of 4-5 students) on addressing a major question in the field will be assigned on the first day. The group work will involve processing information from lectures and discussions during the course, literature searching and applying the students’ own expertise. The groups will be working on their task throughout the week and presenting their work on the last day of the course. Course director Bo Porse, Professor, The Finsenlab/BRIC/DanStem, bo.porse@finsenlab.dk Teachers Dominique Bonnet, Francis Crick Institute Marcel van den Brink, Memorial Sloan Kettering Cancer Center, USA Lars Bullinger, Charité, Germany Ruud Delwel, Erasmus MC, the Netherlands Kirsten Grønbæk, BRIC/Rigshospitalet Bo Porse, BRIC/Rigshospitalet Henrik Sengeløv, Rigshospitalet Liran Shlush, Weissman Institute, Israel Kim Theilgaard-Mönch, BRIC/Rigshospitalet Norbert Vey, Institut Paoli-Calmettes, France Krister Wennerberg, BRIC Petter Woll, Karolinska Institutet, Sweden Dates October 21-25, 2019 Course location Biotech Research and Innovation centre Registration Please register before September 1st 2019 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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