Graduate School of health and Medical Sciences

The role of the microbiome in complex metabolic and inflammatory diseases
Provider: Faculty of Health and Medical Sciences

Activity no.: 3674-19-00-00
	Enrollment deadline: 02/08/2019

Date and time	30.09.2019, at: 09:00 - 02.10.2019, at: 16:00
Regular seats	24
Course fee	4,560.00 kr.
ECTS credits	2.50

Contact person	Camilla Verdich E-mail address: cave@sund.ku.dk


Aim and content Special rules apply for this course. Registration takes place through the Danish Diabetes Academy. Find the link below under "Registration" This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from Nordic countries. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives The purpose of the Autumn School is to gather experienced and young researchers in the different fields of microbiome research in relation to metabolic and inflammatory diseases and to allow for establishing network and collaborations across borders. A student who has met the objectives of the course will be able to: 1. Demonstrate a basic understanding of the microbiome composition, incl. the oral, gut and skin microbiome 2. Discuss the role of the microbiome in complex metabolic and inflammatory diseases 3. Explain host-microbiome interactions 4. Define appropriate applications of state-of-the-art (e.g. sequencing) laboratory techniques to study the microbiome 5. Describe the application of statistical and bioinformatics methods to evaluate scientific result 6. Identify potential approaches of modifying the microbiome towards health benefits. Content Lectures are given on the following topics/tentative titles: • Evolutionary perspectives on the gut microbiome (Prof John Baines) • The role of the diet in the microbiome (Prof. Tine Rask Licht) • Statistical Analysis of Human Microbiome Studies (Prof Astrid Dempfle) • The different elements of the microbiome incl. bacteriophages (Prof. Dennis Sandris Nielsen) • Industry approach to clinical microbiomics, has accepted will stay for the whole period (Henrik Bjørn Nielsen, Chief Scientific Officer, Clinical Microbiomics). • Microbiome and immune system (Professor Susanne Brix Pedersen) • Regulation of tolerance and inflammation by human antigen-specific T cells (Prof Petra Bacher) • The innate immune system vs. microbiome & intestinal organdies as a model system (Prof Philip Rosenstiel) • Microbiome in Metabolism ( Speaker TBA) • Bile acid metabolism (Prof. Jörg Heeren) Keynote lectures in the area of Microbiome in complex metabolic and inflammatory diseases • Colin Hill, working in the area of Molecular Microbiology, particularly in issues involving infection. • TBA • TBA Workshops (four 3 hour workshops held in parallel) on: • Design of human intervention studies to investigate the microbiome in complex metabolic and inflammatory diseases • Best practice in bioinformatics of microbiome data • Data integration of microbiome and other data • Culturomics Presentations from the PhD Students A total of 50-60 “1-minute flash talks” from each of the attendants on their current research project, followed by in-depth discussions during poster sessions. Participants PhD students across a scientific domains of biomedical and natural sciences including, but not restricted to medicine, molecular biology, biology, microbiology, food and nutrition. It is expected that the participating PhD students are themselves involved in research on the microbiome or in a related field of relevance to the area. PhD students are asked to provide a CV and a motivation letter upon registering for the PhD School. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: Basic Metabolic Research Biostatistics and Bioinformatics Cardiovascular Research Language: English Form Lectures, workshops, short flash talks and poster presentations by all attendants, scientific networking activities. Course director Torben Hansen, Professor NNF Center for Basic Metabolic Research Human Genomics and Metagenomics in Metabolism Blegdamsvej 3B, 2200 Copenhagen N, Maersk Tower, Building: 07-8-26 torben.hansen@sund.ku.dk Teachers giving lectures 1. Professor Dennis Sandris Nielsen, KU SCIENCE, Denmark 2. Professor Susanne Brix Pedersen, Danish Technical University, Denmark 3. Professor Tine Rask Licht, Danish Technical University, Denmark 4. Henrik Bjørn Nielsen, Chief Scientific Officer, Clinical Microbiomics. Denmark 5. Professor John Baines, Institute of Experimental Medicine, Max-Planck Institute for Evolutionary Biology, Plön, Germany 6. Professor Astrid Dempfle Institute of Medical Informatics and Statistics, University Medical Center Schleswig-Holstein, Kiel, Germany 7. Professor Petra Bacher, Institute for Clinical Molecular Biology, Kiel, Germany 8. Professor Philip Rosenstiel, Institute for Clinical Molecular Biology, Kiel, Germany 9. Professor Jörg Heeren, University Medical Center Hamburg-Eppendorf, Germany Invited speakers giving a Keynote lecture • Keynote: Dr Colin Hill University College Cork. Ireland • Keynote: TBA • Keynote: TBA Teachers involved as workshop instructors, chair of lectures, facilitating network activities etc. • Professor Andre Franke, Institute of Clinical, Molecular Biology, Kiel University • Professor Thomas Clavel (tbc) , Universitätsklinikum Aachen, Germany • Dr Malte Rühlemann, Institute for Clinical Molecular Biology, Kiel, Germany • Dr Lucas Moitinho-Silva, Institute for Clinical Molecular Biology, Kiel, Germany • Dr Louise Thingholm, Institute for Clinical Molecular Biology, Kiel, Germany • Dr Felix Sommer, Institute for Clinical Molecular Biology, Kiel, Germany • Professor Jan Rupp, Department of Infectiology and Microbiology, UKSH, Lübeck, Germany • Postdoc Thorsten Brach, KU SUND, CBMR, Denmark • Professor Torben Hansen, KU SUND, CBMR, Denmark • Associate Professor Manimozhiyan Arumugam, KU SUND, CBMR, Denmark • Professor Karsten Kristiansen, KU SCIENCE, Denmark • Henrik Bjørn Nielsen, Chief Scientific Officer, Clinical Microbiomics. Denmark • Professor Philip Rosenstiel, Institute for Clinical Molecular Biology, Kiel, Germany • Professor Karsten Kristiansen, KU SCIENCE, Denmark Dates 30.09 - 02.10 2019 (We recommend arrival the September 29 around 18 hrs for dinner) Course location Gl. Avernæs Sinatur Hotel & Konference, Helnæsvej 9, 5631 Ebberup, Fyn Registration Please register before June 18 Please register via the Danish Diabetes Academy website here Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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