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Infection Microbiology: Antimicrobial Resistance and Molecular Typing
Provider: Faculty of Health and Medical Sciences
Activity no.: 3125-20-00-01
Enrollment deadline: 28/08/2020
Date and time
28.09.2020, at: 09:00 - 09.10.2020, at: 16:00
Regular seats
16
Course fee
13,920.00 kr.
Lecturers
Rikke Heidemann Olsen
ECTS credits
6.00
Contact person
Rikke Heidemann Olsen E-mail address: cava@sund.ku.dk
Enrolment Handling/Course Organiser
PhD administration E-mail address: phdkursus@sund.ku.dk
Aim and content
This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee.
Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from Nordic countries. After the enrollment deadline, available seats will be allocated to applicants on the waiting list.
Learning objectives
A student who has met the objectives of the course will be able to:
1. Knowledge: Evaluate the different tools used to identify and type antimicrobial resistant in bacteria
2. Knowlegde: Interpretation of whole genome sequencing data and what can one do with such data
3. Skills: Hands on experience with different antimicrobial resistance testing methods used in clinical microbiology diagnostic and research labs
4. Skills: Hands on experience with different typing methods including next generation sequencing and bioinformatics analysis
5. Competences: Knowledge gained can be extrapolate to other bacteria species
Content
This course provides an introduction to antimicrobial resistance and how we measure resistance. The significance and impact of antimicrobial resistance in human and veterinary medicine, and the Danish agricultural industry are also covered.
We will introduce participants to basic concepts and current methods used for antimicrobial resistance testing and bacterial strain typing. Within the area of antimicrobial resistance, both phenotypic (antimicrobial susceptibility testing and detection of specific resistance phenotypes of clinical importance) and genotypic (identification and typing of resistance genes and their associated mobile genetic elements) analyses will be addressed by lectures and lab practicals. Furthermore, in the lab, we will attempt to evolve antimicrobial resistance in clinically significant bacteria as well as investigating non-antibiotic alternative strategies to fight antibiotic resistant infections e.g. bacteriophages. For bacterial typing, we will cover commonly used molecular techniques we use in our lab, including sequence-based methods e.g, single gene sequencing (S. aureus spa typing) and whole genome sequencing.
The theoretical and practical teaching is concentrated in a 2-week period. Lectures and laboratory exercises are integrated and linked to 2-3 real life clinical case stories (problem-based learning) to make the course more interesting, stimulating and relevant. In addition, students will be given a basic introduction to some commonly used bioinformatics tools e.g. QC of NGS data, sequence assembly and alignment, determining MLST types, in silico antibiotic resistance determination, and analysis of bacterial whole genome sequencing data, and have an opportunity to spend an afternoon with an epidemiologist to learn about good epidemiological study designs.
Participants
PhD students require a basic knowledge of microbiology
Relevance to graduate programmes
The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH:
All Graduate Programmes
Language
English
Form
Lectures, laboratory work, group discussions, journal club, poster presentations
Course director
Arshnee Moodley, asm@sund.ku.dk, Department of Veterinary and Animal Sciences/Section for Veterinary Clinical Microbiology
Teachers
Staff at the Department of Veterinary and Animal Sciences as well as scientists from other research institutions in Denmark and from other countries
Dates
28 September - 9 October 2020
Course location
Department of Veterinary and Animal Sciences, Stigbøjlen 4, 1870 Frederiksberg C
Registration
Please register before 28 August 2020
Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules.
Applications from other participants will be considered after the last day of enrolment.
Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.
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