Graduate School of health and Medical Sciences

Tracing brain and behavioural changes across the life span: Influence of intrinsic and extrinsic factors and personalized health care
Provider: Faculty of Health and Medical Sciences

Activity no.: 3244-20-00-00
	Enrollment deadline: 01/01/2020

Date and time	27.01.2020, at: 09:00 - 31.01.2020, at: 16:00
Regular seats	30
Course fee	5,400.00 kr.
Lecturers	Hartwig Siebner
ECTS credits	3.60

Contact person	Susanne Steffensen E-mail address: susannes@drcmr.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from Nordic countries. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1. Define typical age-related changes in human behaviour, e.g. cognitive and emotional functions, across the lifespan. 2. Define typical age-related changes in the human brain across the lifespan 3. Have insight into how intrinsic factors, such as genes and hormones, may influence brain and behaviour across the lifespan 4. Have insight into how extrinsic factors, such as physical activity, stress, physical environment may influence on brain and behaviour across the lifespan. 5. Have insight into how neurological and psychiatric disorders may affect age-related changes in brain and behaviour 6. Have insight into how neurological and psychiatric disorders may affect age-related changes in brain and behaviour 7. Have insight into modelling techniques to analyse longitudinal multimodal data 8. Identify some of the strengths, challenges and pitfalls when performing and analysing multimodal cohort studies across the life span 9. Have insight in the underpinnings, potential and implementation of personalized/precision medicine approaches. Content Insight into how the human brain and behaviour changes and is affected by biological, bodily or physical, and environmental factors, across the life span is pivotal in understanding behavioural and neurobiological risk for pathology, and for understanding health, resilience and potential. Lectures are given by experts in the field and build on the latest research findings from neuroimaging and behavioural studies. The course highlights specific intrinsic, e.g. genes, hormones, immune system and extrinsic factors, e.g. nutrition, gut microbiota and physical activity, which influence brain and behavioural development and aging. Deviations from the typical pattern of brain and behavioural trajectories are illustrated by examples of neurological and psychiatric disorders. We will address fundamental methodological and neuroscientific questions regarding life-span neuroscience. Study designs and data analytical approaches. What is a “good” or “bad” life-span trajectory in terms of brain function and structure? How do we work towards more personalized, precision medicine optimised to individuals? How does a given brain function unfold over long time-window and how can these behavioural trajectories be linked to “brain dynamics” in terms of structural and functional changes? Main themes Day 1: Population neuroscience across the lifespan Day 2: Brain and behavioural changes across the human life span Day 3: Identifying patterns of change over time and causality: data analyses strategies Day 4: Intrinsic and extrinsic factors influencing brain and behaviour across the lifespan Day 5: Towards personalized health care Programme For the preliminary programme please click here Participants PhD students (e.g. medicine, neuroscience, psychology, engineering, humanities) interested in brain and behavioural changes across the life span. No specific qualifications required. There is room for maximal 30 students Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: Neuroscience Public Health and Epidemiology Language English Form Lectures, group work, discussions Course director Carl Johan Boraxbekk, Professor, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark and University of Umeå, cj@drcmr.dk Kathrine Skak Madsen, Senior researcher, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark and Radiography, Department of Technology, University College Copenhagen, Copenhagen, Denmark, kathrine@drcmr.dk Hartwig Siebner, Professor, Danish Research Center for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark; Department of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark; Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark, h.siebner@drcmr.dk William F.C. Baaré, Senior Researcher, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark, wimb@drcmr.dk Teachers Andrew Schork, Lead Scientist, Institute of Biological Psychiatry, Mental Health Services, Sct. Hans, Copenhagen, Capital Region, Denmark Anne-Marie Nybo Andersen,Professor, Section Epidemiology, department of Public Health, University of Copenhagen, Denmark Anouk Marsman, Senior Researcher, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark Athanasia Monika Mowinckel, Staff Scientist, Center of Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Norway Carl-Johan Boraxbekk, Professor, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark& University of Umeå Carsten Obel, Professor, Department of Public Health - Institute of General Medical Practice, Aarhus University, Denmark Claudia Buss, Professor, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Institute of Medical Psychology, Berlin, 10117, Germany & University of California, Irvine, Development, Health, and Disease Research Program, Orange, CA, 92697, USA Danilo Bzdok, Professor, Section of Social and Affective Neurosciences, Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Germany Hartwig Siebner, Professor, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark & Department of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark & Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark Kathrine Skak Madsen, Senior Researcher, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark & Radiography, Department of Technology, University College Copenhagen, Copenhagen, Denmark Kristine Walhovd, Professor, Center of Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Norway Laura Nawijn, Reseacher, Department of Psychiatry, VU university Medical Center, Amsterdam, the Netherlands Petra Sandberg, Postdoc, Centre for Demographic and Aging Research, Department of Psychology, Umeå University, Umeå, Sweden Rochellys Diaz Heijtz, Associate Professor, Department of Neuroscience, Karolinska Institute, Sweden Rogier Kievit, Group leader, MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK Søren Brunak, Professor, Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark Tomáš Paus, Professor, Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Canada & Departments of Psychology and Psychiatry, University of Toronto, Toronto, Canada Victoria Southgate, Professor, Department of Psychology, University of Copenhagen, Copenhagen, Denmark William Baaré, Senior Researcher, Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark Dates 27 - 31 January 2020 Course location Educational building auditorium A1, and rooms 1 and 4 Hvidovre Hospital Kettegård Allé 30 DK-2650 Hvidovre Denmark Registration Please register before 1 January 2020 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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