Graduate School of health and Medical Sciences

CONVERTED TO ONLINE DUE TO COVID-19 - Drug synthesis
Provider: Faculty of Health and Medical Sciences

Activity no.: 3680-20-00-00
	Enrollment deadline: 01/03/2020

Date and time	04.05.2020, at: 08:30 - 18.05.2020, at: 17:00
Regular seats	12
Course fee	7,560.00 kr.
Lecturers	Trond Ulven
ECTS credits	3.60

Contact person	Marianne Wieslander Jørgensen E-mail address: marianne.joergensen@sund.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from Nordic countries. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1. Design rational and efficient routes to target compunds, including routes suitable for optimization and routes suitable for large-scale production 2. Acqure overview over and critically evaluate existing routes to targets (from hits to APIs) 3. Demonstrate in-depth understanding of common useful reactions in medicinal chemistry, includig reaction mechanisms, scope and limitations 4. Demonstrate in-depth understanding of specially covered topics, including metal-catalyzed cross-coupling reactions, photoredox chemistry, and late-stage functionalization Content The course will contain advanced contemporary synthetic methods in medicinal chemistry, including design of synthetic routes for different purposes (e.g. synthesis of specific analogues, libraries, upscaling), retrosythetic analysis, practical factors, environmental factors and safety. The students will be trained in analysis of synthetic routes from the literature and in design new synthetic routes. Contemporary topics will be covered, include cross-coupling reactions, photoredox synthesis, late-strage functionalization, and automated synthesis Participants The target group is PhD students withing medicinal chemistry, organic chemistry and related areas. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: Pharmaceutical Sciences (Drug Research Academy) All graduate programmes Language English Form The course will consist of lectures, discussions, exercises, group work, and presentations from the participants. Course director Trond Ulven, Professor, Department of Drug Design and Pharmacology, tu@sund.ku.dk Teachers Trond Ulven. Professor, ILF, SUND Lennart Bunch. Associate Professor, ILF, SUND Matthias Herth. Associate Professor, ILF, SUND Jesper Kristensen. Professor, ILF, SUND Andreas Ritzén, Senior Principal Scientist, Leo Pharma Dates 4 - 6 May 2020 Course location Department of Drug Design and Pharmacology Faculty of Health and Medical Sciences Jagtvej 162 2100 Copenhagen OE Denmark Registration Please register before 15 Febuary 2020 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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