Graduate School of health and Medical Sciences

Development, application and clinical translation of molecular imaging probes
Provider: Faculty of Health and Medical Sciences

Activity no.: 3169-21-00-00
	Enrollment deadline: 01/08/2021

Date and time	30.08.2021, at: 09:00 - 17.09.2021, at: 16:00
Regular seats	15
Course fee	8,160.00 kr.
Lecturers	Matthias Herth
ECTS credits	7.50

Contact person	Marianne Wieslander Jørgensen E-mail address: marianne.joergensen@sund.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from Nordic countries. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1. describe the principles of macroscopic in vivo molecular imaging methods such as PET, SPECT, MRI and fluorescence imaging 2. compare molecular imaging methods in terms of information they provide, risks for the patient and practical limitations 3. list key steps of molecular imaging agent development workflow 4. formulate the criteria that should be satisfied by an imaging agent for a given target and imaging modality 5. critically analyze the strenghts and weaknesses of a given molecular imaging agent Content Molecular imaging methods make it possible to visualize and quantify physiological and pathological processes in vivo in a non-invasive manner. Therefore, they have a wide array of applications including fundamental biomedical research, drug development, disease diagnostics and treatment monitoring. Molecular imaging relies on molecular probes which can be endogenous (e.g. water or oxyhemoglobin) or exogenous. Imaging agents typically contain a label which produces a signal (radioactivity, fluorescence, magnetization etc.) that can be followed by an external imaging device. The course curriculum includes: - a comparative overview of macroscopic molecular imaging methods (modalities) and their relative advantages and drawbacks. The main focus lies on nuclear imaging (SPECT and PET), fluorescence and magnetic resonance imaging - applications of molecular imaging in research and development as well as in clinical practice - an in-depth treatment of the design of molecular imaging agents, covering the types of labels that can be used, the chemistry necessary to introduce them and the physico-chemical properties that determine the success or failure of an imaging agent - aspects of clinical translation of molecular imaging probes Participants This course will be especially beneficial for students interested in drug design and molecular imaging and having a basic understanding of organic chemistry and pharmacology. Academic qualification equivalent to an MSc degree is recommended. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: Medical and Molecular Imaging Pharmaceutical Sciences (Drug Research Academy) Clinical Cancer Research Language English Form The course is based on lectures, exercises and project work. Workload: Lectures - 43 hours Exercises - 10 hours Preparation connected to lectures and exercises - 79.5 hours Project work - 55 hours The project work will include finding and analyzing information about imaging probes for a certain application and preparing a 20 min pitch presentation highlighting the advantages of a certain probe over its alternatives. The probes and applications to be investigated will be assigned by the teacher. The students will be split into groups of 2-3 to work on the project assignment and will be given one week after the last lecture of the course to prepare their pitch presentations. The course will end with a pitch competition among the groups. If students from outside Copenhagen apply for this course, pitch competition can be partially or fully conducted online. Course director Matthias Manfred Herth, Associate Professor, Department of Drug Design and Pharmacology, University of Copenhagen, matthias.herth@sund.ku.dk Teachers Matthias Herth, Associate Professor, Department of Drug Design and Pharmacology, KU Vladimir Shalgunov, Assistant Professor, Department of Drug Design and Pharmacology, KU Christian Bernard Matthijs Poulie, Postdoc, Department of Drug Design and Pharmacology, KU Mikael Palner, Junior Group Leader, Neurobiology Research Unit Robin de Nijs, Medical Physicist, Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet Jesper Tranekjær Jørgensen, Assistant Professor, Cluster for Molecular Imaging/Department of Clinical Physiology, Nuclear Medicine and PET, department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet (to be confirmed) Benny Bang-Andersen, Senior Director at Lundbeck (to be confirmed) Yuki Mori, Core Director, Center for Translational Neuromedicine Dates 30 August - 3 September and 16-17 September 2021 Course location Department of Drug Design and Pharmacology, University of Copenhagen Registration Please register before 1 August 2021 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

Click the search button to search Courses.

See which courses you can attend and when

Jan	Feb	Mar	Apr
May	Jun	Jul	Aug
Sep	Oct	Nov	Dec

New courses
Courses are published regularly. High demand courses are announced in spring and autumn.

Learn which courses are announced on fixed dates