Graduate School of health and Medical Sciences

Organoid technology - a practical course
Provider: Faculty of Health and Medical Sciences

Activity no.: 3696-21-00-00	There are no available seats
	Enrollment deadline: 25/10/2021

Date and time	22.11.2021, at: 09:00 - 26.11.2021, at: 17:00
Regular seats	12
Course fee	11,280.00 kr.
Lecturers	Kim Bak Jensen
ECTS credits	4.10

Contact person	MoMed Team E-mail address: momed@bric.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD students at graduate schools in the other Nordic countries. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from Nordic countries. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1. Understand the basis for tissue maintenance 2. Understand how this knowledge can be applied to establish organoid cultures 3. Obtain the practical skills to derive, culture and assess organoids from a range of tissues 4. Design experiments harnessing the advantages of organoid technology 5. Analyse and interpret results from experiments involving organoid technology 6. A broad overview of the field of organoids and its current strengths and limitations Content The course will cover the essential steps towards a deeper understanding of how adult tissues are maintained by stem cells and how it is possible to harness their potential by the derivation of organoid cultures directly from tissues in order to address critical biological questions. The historical perspective will reveal how insights from various in vivo studies paved the way for outlining essential factors necessary firstly, for the derivation and expansion of primary cells and secondly, for the differentiation into functional cell lineages in vitro. The theoretical part of the course will cover research over the last 10 years starting from the inception of organoid technologies from tissues as well as pluripotent stem cells to the developments in bioengineering and clinical applications of organoids. The practical part will include establishing organoids from a range of tissues, maintaining organoids in culture, and how imaging can be utilised as a beneficial read-out for assessing primary cell behaviour. Specifically, we will cover: 1) Introduction to organoids 2) Organoids derived from primary tissues 3) Organoids derived from pluripotent stem cells 4) Next-generation organoid technology 5) Clinical applications 6) From tissues to image read-out - practical sessions Participants A requirement for participation is prior experience with maintaining sterile cultures of mammalian cells. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: Molecular Mechanisms of Disease Basic Metabolic Research Pharmaceutical Sciences (Drug Research Academy) Language English Form Lectures, discussions and pratical exercises Course director Kim B. Jensen, Professor, BRIC, Univerisity of Copenhagen, kim.jensen@bric.ku.dk Teachers Hjalte L. Larsen, Assistant professor, BRIC, Univerisity of Copenhagen, hjalte.larsen@bric.ku.dk Martti Maimets, Assistant professor, BRIC, Univerisity of Copenhagen, martti.maimets@bric.ku.dk Svetlana Ulyanchenko, Assistant professor, BRIC, Univerisity of Copenhagen, svetlana.ulyanchenko@bric.ku.dk Dates 22 - 26 November 2021 Course location BRIC, Biocenter, Ole Maaloes Vej 5. Registration Please register before 25 October 2021 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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