Graduate School of health and Medical Sciences

Introduction to omics for clinical researchers part 2
Provider: Faculty of Health and Medical Sciences

Activity no.: 3689-22-00-01
	Enrollment deadline: 18/12/2022

Date and time	10.05.2023, at: 09:00 - 12.05.2023, at: 16:00
Regular seats	25
Course fee	2,640.00 kr.
Lecturers	Lise Lotte Gluud Nicolai Jacob Wewer Albrechtsen
ECTS credits	1.90

Contact person	Lise Lotte Gluud E-mail address: lise.lotte.gluud.01@regionh.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD Students from NorDoc member universities. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from NorDoc member universities. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1.Knowledge (part 1): understand and discuss the fundamental principles underlying OMICS analyses including genomics, transcriptomics, proteomics, and lipidomics as well as bioinfomatics. 2.Knowledge (part 2): understand and discuss key aspects of the methods, techniques and interpretation of applied OMICs analyses including i) the impact of genome variation on health and disease, ii) the potential applications of modern techniques to study genomic variation, iii) the strengths and limitations of translation of genome variation, iv) the application of RNA sequencing, v) the principles and application of transcriptomic profiling of tissue and single cells, vi) the application, characteristics and principles of proteomics, vii) the use of mass spectrometry for proteomic analyses and protein databases, viii) the characteristics and principles of metabolomics, ix) the basic aspects of bioinformatics including machine learning, integration of omic data and visualization. 3.Skills (part 1): Understand and discuss the fundamental aspects of studies using genomics, transcriptomics, proteomics, metabolomics and bioinformatics in humans. 4.Skills (part 2): i) Critically evaluate results from studies of genomics, transcriptomics, proteomics, metabolomics and bioinformatics in humans, ii) Design an appropriate study evaluating OMICS in human diseases. 5.Competences (part 1): Understand and explain central aspects of key aspects of OMICS studies. 6.Competences: Understand and explain central aspects of applied OMICS studies (part 2). Content The main themes covered in the course are genomics, transcriptomics, proteomics, metabolomic and bioinformatics. Part 1 covers the fundamental aspects and part 2 includes more detailed knowledge including applied OMICS studies. Participants Participants must be enrolled as PhD students at the Copenhagen University, Faculty of Health and Medical Sciences, University of Copenhagen. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: - All graduate programmes Language English Form The course is organized as an 10.5-hour online course (part 1) followed by a 3-day course with lectures (part 2). Both courses include exercises. We recommend that part 1 is completed before enrolment in part 2, but the two courses may be taken independently. The plan is to record part 1 as an online course consisting of modules that may be taken by the students when it is convenient for them. This is done to increase the flexibility and will also make it possible for a larger number of students to enrol. Participants may enrol as soon as the course becomes available and complete the course at a date that suits them (similar to the MOOC format). At the end of each online module, participants have to compete multiple choice questionnaires to ensure that the course is interactive. Course director - Lise Lotte Gluud, Professor, Copenhagen University Hospital Hvidovre, University of Copenhagen, lise.lotte.gluud.01@regionh.dk - Nicolai J. Wewer Albrechtsen , Associate Professor, Novo Nordisk Foundation, Center for Protein Research, University of Copenhagen, nicolai.albrechtsen@sund.ku.dk Teachers - Stefan Stender, Stefan.Stender@regionh.dk, Senior Registrar, Department of Clinical Biochemistry, Rigshospitalet, - Peter Davidsen, pedv@novonordisk.com, Computational Biologist, Bioinformatics and Data Mining, - Lili Niu, lili.niu@cpr.ku.dk, PhD student, Novo Nordisk Foundation Center for Protein Research, Clinical Proteomics, University of Copenhagen, - Karolina Sulek, karolina.sulek@cpr.ku.dk, Associate Professor, Mann Group, University of Copenhagen, - Tune H Pers, tune.pers@sund.ku.dk, Associate Professor, Novo Nordisk Foundation, Center for Basic Metabolic Research, University of Copenhagen, - Torben Hansen, torben.hansen@sund.ku.dk, Professor, Novo Nordisk Foundation, Center for Basic Metabolic Research, University of Copenhagen, - Karina Banasik, karina.banasik@cpr.ku.dk, Associate Professor, Novo Nordisk Foundation Center for Protein Research, Brunak Group, - Andreas Mund, andreas.mund@cpr.ku.dk, Associate Professor, Novo Nordisk Foundation Center for Protein Research,Proteomics Program, - Ana Rita Freitas Colaco, rita.colaco@cpr.ku.dk, PostDoc, Novo Nordisk Foundation Center for Protein Research,Proteomics Program, - Annelaura Bach Nielsen, annelaura.bach@cpr.ku.dk, PostDoc, Novo Nordisk Foundation Center for Protein Research,Proteomics Program - Filip Oskar Mundt, filip.mundt@cpr.ku.dk, PostDoc, Novo Nordisk Foundation Center for Protein Research,Proteomics Program b>Dates Part 1: the online course will be available in March 2023. Part 2: will take place 10-11 May 2023. The plan is to update part 1 annually and repeat part 2 once yearly. Course location Kommunehospitalet, University of Copenhagen Registration Please register before: Part 1: 1 November 2022. Part 2: 18 December 2022 (for the course in May 2023) Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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