Graduate School of health and Medical Sciences

Mass Spectrometry (MS)-based proteomics and its applications in biology
Provider: Faculty of Health and Medical Sciences

Activity no.: 3624-22-00-00
	Enrollment deadline: 09/10/2022

Date and time	14.11.2022, at: 09:00 - 18.11.2022, at: 17:00
Regular seats	30
Course fee	6,120.00 kr.
Lecturers	Michael Lund Nielsen
ECTS credits	4.00

Contact person	MoMed Team E-mail address: momed@bric.ku.dk

Enrolment Handling/Course Organiser	PhD administration E-mail address: phdkursus@sund.ku.dk

Aim and content This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD Students from NorDoc member universities. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from NorDoc member universities. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1. Gain insights into the major high-end proteomics technologies and workflows 2. Ability to design quantitative proteomics experiments to address questions in biology 3. Analyze mass spectrometric data of peptides and proteins 4. Understand in which biological applications that quantitative proteomics can be applied 5. Gain insights into computational proteomics tools Content Basics about proteomics: MS technologies (orbitrap instrumentation and fragmentation mechanisms for peptide sequencing), Quantitative MS (SILAC, TMT and Label free), proteomics sample preparation methods, computational proteomics software and analysis strategies. Applications of quantitative proteomics in biology: Large-scale proteome mapping of model organisms, Epigenetics and proteomics, stem cell biology, In-vivo SILAC, Large-scale phosphoproteomics, Other PTMs, Computational proteomics, organellar proteomics, protein-protein interaction screens, and protein-PTM interactions. Participants Maximum 24 PhD students with interest in proteomics, precision medicine, protein research, cell biology, cell signaling, omics technologies. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: - All graduate programmes Language English Form A mixture of lectures, data analysis exercises, journal clubs (presented by the participating students) and scientific seminars by invited, international speakers. Technical lectures about modern proteomics technologies used to study cellular signaling pathways, protein-protein interactions and global proteome changes. Course directors Michael Lund Nielsen, Professor, Novo Nordisk Foundation Center for Protein Research (CPR), Faculty of Health and Medical Sciences (SUND), University of Copenhagen (UCPH), michael.lund.nielsen@cpr.ku.dk Jesper Velgaard Olsen, Professor, Novo Nordisk Foundation Center for Protein Research (CPR), Faculty of Health and Medical Sciences (SUND), University of Copenhagen (UCPH), jesper.olsen@cpr.ku.dk Chunaram Choudhary, Professor, Novo Nordisk Foundation Center for Protein Research (CPR), Faculty of Health and Medical Sciences (SUND), University of Copenhagen (UCPH), chuna.choudhary@cpr.ku.dk Teachers Matthias Selbach (Prof., MDC-Berlin); Michiel Vermeulen (Prof., Univ. Radboud Universiteit Nijmegen); Shabaz Mohammed (Prof., Oxford university); Boris Macek (Professor, Univ. Tuebingen); Tiziana Bonaldi (Gr. Leader, European Institute of Oncology); Jürgen Cox (Max-Planck Institute for Biochemistry, Munich); Marcus Krüger (Max-Planck Institute Cologne); Janne Lethiö (Karolinska Institute, Stockholm); Richard Scheltema, (Utrecht University), Frank Kjeldsen (Professor, University of Southern Denmark); Jens S. Andersen, (Professor, University of Southern Denmark); Blagoy Blagoev (Professor, University of Southern Denmark); Jesper V. Olsen, Professor, CPR, SUND, UCPH; Michael Lund Nielsen, Professor, CPR, SUND, UCPH; Chunaram Choudhary, Professor, CPR, SUND, UCPH; Atul Deshmukh, Ass. Professor, CPR, SUND, UCPH; Enrico Cappellini, Ass. Professor, GLOBE, ECPH Lars J. Jensen, Professor, CPR, SUND, UCPH; Dates Nov. 14-18, 2022, all days 9-17 Course location Novo Nordisk Foundation Center for Protein Research, room 6.2.09 Registration Please register before October 9th , 2022 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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