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Applied Toxicology
Provider: Faculty of Health and Medical Sciences

Activity no.: 3152-19-00-00 
Enrollment deadline: 14/12/2018
Date and time14.01.2019, at: 09:00 - 01.02.2019, at: 16:00
Regular seats12
Course fee12,600.00 kr.
LecturersKlas Abelson
ECTS credits7.50
Contact personGitte Balle Kaltoft    E-mail address: gitte.nielsen@sund.ku.dk
Enrolment Handling/Course OrganiserPhD administration     E-mail address: fak-phdkursus@sund.ku.dk

Aim and content
This course is free of charge for PhD students at Danish universities (except Copenhagen Business School). Special rules apply for research year students enrolled at Faculty of Health and Medical Sciences at UCPH. All other participants must pay the course fee.
Anyone can apply for the course, but if you are not a PhD student, you will be placed on the waiting list for the course until enrollment deadline. After the deadline of enrollment, available seats will be allocated to students on the waiting list.

Course title
Applied Toxicology

Learning objectives
A student who has met the objectives of the course will be able to:

1. Know about various areas of regulation of chemicals
2. Know about guideline methods

1. Assess toxicological studies for quality and reliability
2. Perform a risk assessment
3. Perform a toxicological necropsy

The Department of Experimental Medicine at the University of Copenhagen, in collaboration with the Technical University of Denmark, offer a postgraduate course in applied toxicology. The focus of the course is on risk assessment of chemical substances. The purpose of the course is to provide a background for work with toxicological risk assessment. Toxicological risk assessments are performed in many areas of regulation, e.g. in the setting of occupational exposure limits, health-based quality criteria for environmental pollutants and toxicological reference values for chemical substances that can be found in food (contaminants, pesticides, food additives, in relation to assessment of cosmetics, and in the preparation or assessment of toxicological evaluations from producers of chemicals or pharmaceuticals.

The various steps in the risk assessment process are presented: Hazard identification and characterisation, exposure assessment and risk characterisation. Relevant international organisations and risk assessment programmes, the individual toxicological endpoints and their test methods and guidance documents, and data retrieval are included.

Specific content is: Toxicological endpoints and guidelines (toxicokinetics, acute toxicity, local irritation, sensitisation, repeated dose toxicity, mutagenicity/genotoxicity, carcinogenicity, toxicity to reproduction and developmental toxicity); elements of guideline studies (necropsy, haematology, clinical chemistry);
practical advice (study planning, how to find data)

PhD students, postgraduates and other academics

Relevance to graduate programmes
The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH:

In Vivo Pharmacology and Experimental Animals
Pharmaceutical Sciences (Drug Research Academy)
Veterinary and Animal Sciences


The course contains theoretical lectures and practical exercises, including a visit to a toxicological test laboratory, a practical exercise in necropsy technique, and homework. The course concludes with a written examination.

Course director
Klas Abelson; Associate Professor, PhD
Department of Experimental Medicine

Highly qualified experts from the Department of Experimental Medicine, DTU National Food Institute, National Research Center for Working Environment, Danish Environmental Protection Agency, and from the pharmaceutical industry.

14 January – 1 February 2019

Course location
Department of Experimental Medicine, Panum Building, Blegdamsvej 3B, 2200 Copenhagen N.

Please register before 21 December 2018

Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules.
Applications from other participants will be considered after the last day of enrolment.

Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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