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Basic Metabolic Research and Critical Thinking
Provider: Faculty of Health and Medical Sciences

Activity no.: 3810-22-00-00
Enrollment deadline: 21/01/2022
Date and time18.02.2022, at: 09:00 - 18.03.2022, at: 16:00
Regular seats25
ECTS credits2.50
Contact personAmelia Ann Green    E-mail address: amelia.green@cpr.ku.dk

Aim and content
Learning objectives
A student who has met the objectives of the course will be able to:

1.Describe emerging themes in basic metabolic research
2.Have a foundation to critically analyze data from primary literature in basic metabolic research
3.Describe common methods used in the characterization of factors influencing metabolism and metabolic disorders
4.Explain how experiments in the primary literature investigating metabolism were performed
5.Evaluate whether or not a particular series of experiments warrants the conclusion made by the authors of a study

The practice of clinical medicine is currently being revolutionized by rapid and extraordinary technological advances in molecular and cellular biology that have led to an unprecedented understanding of the molecular basis of human disease. Translating this knowledge into new clinical procedures and treatments demands a deeper understanding of the regulation of metabolism, and factors disposing individuals to metabolic disorders.

Metabolic disorders, including type 2 diabetes and obesity, affect hundreds of millions of people worldwide. Basic research investigating the genomic, gut microbiomic, molecular and physiological regulation of metabolism contributes to the progress of translational research within medicine and provides important insights that may be used in developing new initiatives for disease prevention, control and treatment.
The course brings together a group of experienced researchers to provide training on how to analyze data and think critically about state-of-the-art techniques for characterizing metabolic disorders and regulation of metabolism. Specifically, the content of the course will focus on discussing primary literature from current topics in metabolic health, the human genome and predisposition to metabolic disorders, endocrine signaling, and molecular regulation of metabolism.

Ph. D. –level students with a B.Sc. and/or M.Sc. degree in any biological science or chemistry may enrol. The course is limited to a maximum of 25 participants.

The course is particularly suitable for early-stage PhD students looking to improve their general knowledge in the field of metabolic research and their abilities to critically analyze literature through reading and active discussion.

Relevance to graduate programmes
The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH:

Basic Metabolic Research


Students will participate in group literature discussion sessions led by leading researchers in several fields of basic metabolic research, from the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen. The course comprises four literature discussion sessions, which take place approx. once per week. A week before each session, a problem set of relevant scientific papers and questions based on their content will be provided. Students must then read the papers critically and submit a written report with the answers to the set questions before the discussion session. The discussion will then be based on the problem set. Evaluation (pass/fail) will take into account participation in discussion sessions and written work.

Course director

Course directors:
Manimozhiyan Arumugam, Associate Professor, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen
Tuomas Kilpeläinen, Associate Professor, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen

Course organiser:
Amelia Green, Programme Coordinator, Copenhagen Bioscience PhD Programme, University of Copenhagen and Technical University of Denmark

Group Leaders from the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen:

Three-hour discussion sessions on the following dates. Extensive reading of current literature (approx. 6-8 hours per session) and preparation of a written report are required in advance of each. Expected dates:
Friday 18 February, 2022
Friday 25 February, 2022
Friday 11 March, 2022
Friday 18 March, 2022
(2.5 ECTS)

We expect that discussion sessions will take place with all participants physically present, and following relevant coronavirus precautions - unless the coronavirus guidelines at the time require classes to be online, in which case the discussion sessions will take place online on the same dates.

Course location
Panum Institute, University of Copenhagen, Norre Alle 20, 2200 København

Please register before 21 January, 2022. Use this form: https://www.tilmeld.dk/cbmrcriticalthinking to provide your name, email address, the university and graduate programme where you are currently enrolled, and a 150 word (max.) statement of your motivation for applying for this course. You will be notified about your registration by email soon after the deadline. Contact amelia.green@cpr.ku.dk with any questions.

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