Graduate School of health and Medical Sciences

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Genome Maintenance and Diseases
Provider: Faculty of Health and Medical Sciences

Activity no.: 3252-27-00-00	There are 20 available seats
	Enrollment deadline: 08/04/2027

Place	Panum Blegdamsvej 3B, 2200 København N
Date and time	10.05.2027, at: 09:00 - 13.05.2027, at: 19:30
Regular seats	20
Course fee	7,800.00 kr.
Lecturers	Julien Duxin Claus Sørensen
ECTS credits	2.90

Contact person	MoMed Team E-mail address: momed@bric.ku.dk

Enrolment Handling/Course Organiser	PhD administration SUND E-mail address: phdkursus@sund.ku.dk

Enrolment guidelines This is a specialised course. This means that 80% of the seats are reserved to PhD students enrolled at the Faculty of Health and Medical Sciences at UCPH and 20% og the seats are reserved to PhD students from other Danish Universities/faculties (except CBS). The course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD Students from NorDoc member faculties. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from NorDoc member faculties. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1. Understand and describe the main pathways of genome maintenance and their molecular links to cancer and other human diseases 2. Understand the benefits and limitations of different model systems and technologies to study genome maintenance processes 3. Analyze experimental data and communicate scientific hypothesis and results 4. Gain a broad perspective of how basic research can be translated into the clinic Content 1. Introduction to genome maintenance pathways and diseases 2. Mechanisms and experimental methods: - DNA Replication stress, protein signaling, and DNA damage response - Imaging, DNA sequencing, structural, and screening technologies 3. Physiology and model organisms: - Modeling genome maintenance diseases in mice - Genome instability in germline cells 4. From basic research to the clinic: - Drug design, validation, and approval - Novel technologies in disease diagnosis - Disease treatment Participants PhD students with an interest in mechanisms of genome maintenance and diseases. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: All graduate programmes Language English Form Lectures Group work and discussions Course director Claus Storgaaard Sørensen, Professor, BRIC, University of Copenhagen, claus.storgaard@bric.ku.dk Julien Duxin, Professor, BRIC, University of Copenhagen, Julien.duxin@bric.ku.dk Teachers Eva Hoffmann, Professor, Center for Chromosome Stability, University of Copenhagen, Haico van Attikum, Professor, Leiden University, Thomas Miller, Associate Professor, Center for Chromosome Stability, University of Copenhagen, Franz Supek, Professor, BRIC, University of Copenhagen, Andy Blackford, Professor, ICMM, University of Copenhagen, Muthiah Bose, RH, Center for Genomic Medicine Arne Nedergaard Kousholt, VUS diagnostics Dates 10 - 13 May 2027 Course location 15th floor, Mærsk Tower, Blegdamsvej 3B, 2200 København N Registration Please register before 8 April 2027 Expected frequency once every 3 years Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment.

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