Graduate School of health and Medical Sciences

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Chromatin biology in development and disease
Provider: Faculty of Health and Medical Sciences

Activity no.: 3579-26-00-00	There are 24 available seats
	Enrollment deadline: 01/09/2026

Date and time	28.09.2026, at: 09:00 - 01.10.2026, at: 16:00
Regular seats	25
Course fee	7,680.00 kr.
Lecturers	Jan Zylicz
ECTS credits	3.00

Contact person	MoMed Team E-mail address: momed@bric.ku.dk

Enrolment Handling/Course Organiser	PhD administration SUND E-mail address: phdkursus@sund.ku.dk

Enrolment guidelines This is a specialised course. This means that 80% of the seats are reserved to PhD students enrolled at the Faculty of Health and Medical Sciences at UCPH and 20% of the seats are reserved to PhD students from other Danish Universities/faculties (except CBS). The course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD Students from NorDoc member faculties. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from NorDoc member faculties. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Learning objectives A student who has met the objectives of the course will be able to: 1. Have a solid understanding of how chromatin is organized and what is epigenetic memory 2. Understand how chromatin and epigenome dynamics operate during mammalian development 3. Analyse and evaluate how chromatin structure influences gene regulation 4. Assess the advantages, limitations, and biological implications of experimental approaches used to study chromatin biology 5. Have an understanding of how chromatin dysregulation contributes to disease Content The course will cover fundamental and advanced concepts in chromatin biology with a focus on how chromatin organisation and epigenetic mechanisms regulate gene expression in development and disease. Participants will be introduced to key principles including nucleosome architecture, histone and DNA modifications, 3D genome folding, enhancer regulation and chromatin inheritance during replication. The course will explore how chromatin landscapes are established, reprogrammed, or disrupted across developmental transitions, as well as how cells maintain genome integrity by controlling transposable elements. In addition, the course will address how chromatin dysfunction contributes to disease, and how environmental cues shape the epigenome. Teaching will be delivered by leading international experts and will include lectures and discussions of current literature. This course is focused on molecular mechanisms underlying chromatin regulation rather than purely clinical work. Participants The course is open to all PhD students interested in learning about the molecular mechanisms of chromatin regulation. A basic understanding of molecular biology is required but no prior knowledge on epigenetics is necessary. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: Molecular Mechanisms of Disease Cellular and Genetic Medicine Clinical Cancer Research Language English Form Lectures, group work, poster presentations. Course director Jan Zylicz, Associate Professor, NNF Center for Stem Cell Medicine, BMI; jan.zylicz@sund.ku.dk Teachers Jan Zylicz, reNEW Kathleen Stewart-Morgan, ICMM Nils Krietenstein, DCI Anja Groth, DCI Daniel Martin Messerschmidt, ICMM Joshua Brickman, reNEW Jonatan Stelzer, Weizman Institute Agnese Loda, Imagine Institue Paris Alex Radzishesskaya, ICR London Daphne Selvaggia Cabianca, Helmholtz Munich Dates 28/09 - 01/10/2026 All days 9-16. Course location Mærsk Tower 7.15.149 Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment. Note: All applicants are asked to submit invoice details in case of no-show, late cancellation or obligation to pay the course fee (typically non-PhD students). If you are a PhD student, your participation in the course must be in agreement with your principal supervisor.

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