Graduate School of health and Medical Sciences

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Mass Spectrometry analysis of glycans, glycoproteins and glycoconjugates
Provider: Faculty of Health and Medical Sciences

Activity no.: 3427-26-00-00	There are 19 available seats
	Enrollment deadline: 04/10/2026

Date and time	02.11.2026, at: 09:00 - 06.11.2026, at: 16:00
Regular seats	20
Course fee	13,080.00 kr.
Lecturers	Sergey Vakhrushev
ECTS credits	3.90

Contact person	Elin Ølgaard Erichsen E-mail address: ee@sund.ku.dk

Enrolment Handling/Course Organiser	PhD administration SUND E-mail address: phdkursus@sund.ku.dk

Enrolment guidelines This course is free of charge for PhD students at Danish universities (except Copenhagen Business School), and for PhD Students from NorDoc member faculties. All other participants must pay the course fee. Anyone can apply for the course, but if you are not a PhD student at a Danish university, you will be placed on the waiting list until enrollment deadline. This also applies to PhD students from NorDoc member faculties. After the enrollment deadline, available seats will be allocated to applicants on the waiting list. Course Description Applications of analytical and synthetic chemistry are fundamental to elucidating the structures and expression patterns of complex biological molecules such as proteins and glycoconjugates, and understanding their functional interactions in order to exploit them effectively as targets of novel diagnostic and therapeutic strategies. This course is intended as an introductory survey of instrumental and chemical techniques currently being applied to proteomics, glycomics, and glycoproteomics, and to biological problems involving protein-carbohydrate interactions. The practical course will include mass spectrometry (MS) applied to the glycopeptide and glycoprotein analysis (bottom up DDA/DIA and Intact MS), with a special focus on key post-translational modifications (PTMs), including N- and O-linked glycosylation. Coverage will include sample preparation, new developments in fragmentation of peptides and glycans for determination of sequence and PTM site occupancy, high throughput applications, biomarker analysis, bottom up and Intact MS analysis, the basics glycoproteomics data analysis. Learning objectives A student who has met the objectives of the course will be able to: 1. Understand the principles of mass spectrometry 2. Describe mechanisms generating glycoproteomic diversity 3. Understand principles of glycoproteomic and PTM analysis 4. Analyse and interpret glycoproteomics datasets Content The following topics are covered on the course: General introduction to mass spectrometry (history, fundamentals), post translational modifications, carbohydrates, glycobiology, glycoproteomics, glycoinformatics and glyco biomedical applications. Participants PhD students engaged in projects that require knowledge of the structural chemistry and intermolecular interactions of glycoconjugates, current methods for analysis of protein glycosylation, and their applications in the field of biomedicine. Relevance to graduate programmes The course is relevant to PhD students from the following graduate programmes at the Graduate School of Health and Medical Sciences, UCPH: All graduate programmes Language English Form Lectures, discussions, exercises and demonstrations Course director Sergey Vakhrushev Associate professor, Copenhagen Center for Glycocalyx Research, Institut for Cellulær og Molekylær Medicin, seva@sund.ku.dk Teachers Sergey Vakhrushev, Copenhagen Center for Glycocalyx Research members and invited external lecturers Dates 2-6 November 2026 Course location Panum, Mærsk Tower, 10th floor Registration Please register before 4 October 2026 Expected frequency The course is offered biennially Seats to PhD students from other Danish universities will be allocated on a first-come, first-served basis and according to the applicable rules. Applications from other participants will be considered after the last day of enrolment.

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